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Immunohistochemical score of Bmi-1 in esophageal adenocarcinoma (EAC). A. No Bmi-1 expression in EAC glands (score 0); B. Bmi-1 weakly positive cells distributed evenly in EAC glands (score 1+); C. Bmi-1 moderately positive cells distributed evenly in EAC glands (score 2+); D. Bmi-1 strongly postive cells are distributed in mostly at the base of EAC glands (score 3+).
