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. 2013 Jan 1;4(1):3–66. doi: 10.4161/viru.22329

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Copyright © 2012 Landes Bioscience

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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graphic file with name viru-4-3-g2.jpg — Figure 2. Schematic representation of cell envelope proteins embedded in the cell wall of the of M. tuberculosis complex. Proteins like Erp, Fbp, HbpA and the porin OmpATb are exposing to the surface. The ABC transporters: Pst-1, Pst-3, Opp and the Mce proteins consist in the substrate binding proteins (SBP), the permeases (MSD) and the nucleotide binding protein (NBD). The two component systems: PhoR-P, DosS/T-R and MprAB consist in the sensor kinase (SK) that senses the stimuli and the response regulator (RR), which induce the gene transcription. AG, arabinogalactan; PG, peptidoglycan; CM, cytoplasmic membrane; TMM, TDM, trehalose mono and di mycolate; DAT, PAT, di and poli acyl trehalose; PGL, phenolic glycolipid; PDIM, phthiocerol dimycocerosate; SL, sulfolipid.