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. 2013 Jan 1;7(1):150–159. doi: 10.4161/cam.22827

Table 1. Laminin-111-derived peptides active with tumor cells, sequence, location and activity.

Peptide/location residues Activity Receptor
YIGSR/β1 929–933
↑ adhesion, ↑ migration, ↓ tumor growth, ↓ metastasis, ↓ invasion
67 kD protein
IKVAV/α1 2097–2108
↑ metastasis, ↑ tumor growth, ↑ angiogenesis, ↑ proteases
integrins α3β1, α6β1
RKRLQVQLSIRT (AG73)/α2620–2631
↑ tumor growth, ↑ metastasis to lung, bone and liver, ↑ invasion, ↑ angiogenesis, ↑ proteases
syndecans 1, 2 and 4
KAFDITYVRLKF (C16)/γ1 139–150 ↑ metastasis, ↑ angiogenesis integrins αvβ3, α5β1