Table 1. Chromosome location of human laminin genes and sizes of the corresponding polypeptides.
Gene name | Chromosome localization | Chain name | Amino acids number* | Molar mass (predicted) |
---|---|---|---|---|
LAMA1 |
18p11.31 |
α1 |
3,075 |
337,084 |
LAMA2 |
6q22-q23 |
α2 |
3,122 |
343,905 |
LAMA3** |
18q11.2 |
α3A |
1,713 |
189,335 |
α3B |
3,333 |
366,649 |
||
LAMA4 |
6q21 |
α4 |
1,823 |
202,524 |
LAMA5 |
20q13.2-q13.3 |
α5 |
3,695 |
399,737 |
LAMB1 |
7q22 |
β1 |
1,786 |
198,038 |
LAMB2 |
3p21 |
β2 |
1,798 |
195,981 |
LAMB3 |
1q32 |
β3 |
1,172 |
129,572 |
LAMB4*** |
7q22-q31.2 |
β4 |
1,161 |
193,540 |
LAMC1 |
1q31 |
γ1 |
1,609 |
177,603 |
LAMC2 |
1q25.31 |
γ2 |
1,193 |
130,976 |
LAMC3 | 9q31-q34 | γ3 | 1,575 | 171,227 |
See http://uniprot.org for more detailed information and relevant references providing sequence data and analysis. *The number of amino acids includes the signal peptide. **The LAMA3 gene encodes two transcripts, the short α3A and the long α3B, sharing identical C-terminus. ***Presumably a pseudogene. Transcripts have not been found.