Table 2. OSA parameters and laboratory profiles.
| non OSA (n = 15) | mild OSA (n = 37) | moderate OSA (n = 24) | severe OSA (n = 26) | p | |
| Parameters of OSA | |||||
| Apnea hypopnea index/h | 2.2±1.6 | 9.4±2.6 | 22.2±5.0a,b | 50.5±19.8a,b,c | <0.01 |
| 4%ODI/h | 1.8±1.6 | 8.2±3.3 | 20.7±6.0a,b | 49.6±20.2a,b,c | <0.01 |
| Minimum SpO2 (%) | 90.3±4.5 | 84.9±4.3 | 78.4±8.6a,b | 71.3±12.2a,b,c | <0.01 |
| Arousal index/h | 24.3±12.1 | 22.8±9.6 | 30.7±13.2 | 43.4±18.3a,b,c | <0.01 |
| Length of time SpO2<90% (m) | 3.2±5.4 | 11.4±17.4 | 37.3±52.2 | 121.1±107.8a,b,c | <0.01 |
| Laboratory profiles | |||||
| FPG (mg/dl) | 107.7±39.9 | 95.4±20.1 | 96.4±24.3 | 102.5±20.2 | 0.35 |
| HbA1c (%) | 5.80±1.22 | 5.49±0.65 | 5.45±0.91 | 5.74±0.86 | 0.45 |
| Total cholesterol (mg/dl) | 185.5±32.3 | 195.2±35.4 | 203.0±44.0 | 201.5±44.0 | 0.53 |
| LDL cholesterol (mg/dl) | 103.2±27.9 | 116.2±27.8 | 118.5±36.8 | 109.5±31.8 | 0.40 |
| HDL cholesterol (mg/dl) | 55.2±12.9 | 52.8±13.5 | 53.0±16.1 | 51.9±13.9 | 0.91 |
| Triglycerides (mg/dl) | 125.1±86.5 | 119.8±58.0 | 139.1±79.1 | 168.0±185.2 | 0.39 |
| BNP (pg/ml) | 14.4±8.7 | 20.6±24.4 | 22.4±31.8 | 21.5±18.7 | 0.73 |
| Creatinine (mg/dl) | 0.72±0.19 | 0.74±0.15 | 0.80±0.17 | 0.78±0.21 | 0.45 |
| Ngal (ng/ml) | 46.9±6.0 | 48.9±10.9 | 51.3±15.2 | 55.4±16.7 | 0.16 |
Data are expressed in mean ± SD or n (%).
OSA: obstructive sleep apnea; ODI: oxygen desaturation index; SpO2: saturation of oxygen; FPG: fasting plasma glucose; LDL: low density lipoprotein; HDL: high density lipoprotein; BNP: brain natriuretic peptide; Ngal: neutrophil gelatinase associated lipocalin.
a
p<0.05 vs non OSA; bp<0.05 vs mild OSA; cp<0.05 vs moderate OSA.