Figure 1. Mutational analysis of the mouse 6C2 MAIT TCR in response to MR1-overexpressing antigen presenting cells.

Response of 6C2 MAIT hybridoma expressing different mutations of the TCR α chain (A, C) or TCR β chain (B, D) to overexpression of mouse MR1 on LM1.8 fibroblasts (A and B) or CH27 B cells (C and D). Data represent the mean+s.e.m. of three independent experiments.