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Voltage dependence of the NMDA-induced plateaus. Current-clamp recording of a rat motoneuron in presence of isradipine (15 μM), TTX (1 μM), and NMDA (100 μM) is shown. This motoneuron exhibited spontaneous NMDA plateaus at rest, which terminated and restarted repeatedly. When the cell was depolarized by injection of a bias current (0.5 nA), the plateaus lasted longer.
