Table 6. Top Significant Biological Functions identified by Ingenuity IPA and literature searches.

Function	p-value range	# Genes
Neurological Disease	2.71E-05 - 3.15E-02	14 (18)
Behavior	5.93E-05 - 4.36E-02	10
Cardiovascular Disease	8.58E-05 - 4.30E-02	10
Cellular Development	1.39E-04 - 4.77E-02	9
Inflammatory response	4.84E-04 - 2.89E-02	6

The right-tailed Fisher's exact test was used to calculate P-values representing the probability that selecting genes associated with that pathway or network is due to chance alone. Each functional category represents a collection of associated subcategories, each of which has an associated P-value. For example, within ‘Neurological Disease,’ are subcategories of genes associated with seizures, Huntington Disease, schizophrenia, etc. The P-value range given represents the range of P-values generated for each subcategory. In the first line, 14 genes were associated with a function in Neurological Disease by Ingenuity software. An additional 4 genes were identified as having neurological functions in the literature, giving a total of 18 with known or suspected roles in neurological disease.