Table 2. Comparison between different endocrine subgroups.
| Hypothyroidism | Hypocortisolism | Hypogonadism | Hyperprolactinemia | |||||
| yes | no | yes | no | Yes | no | yes | no | |
| N. | 42 | 13 | 45 | 10 | 46 | 9 | 20 | 35 |
| Percent (%) | 76.36 | 23.63 | 81.81 | 22.22 | 83.63 | 16.36 | 36.36 | 63.63 |
| Age(year) | 19.64±6.92 | 19.23±6.31 | 18.82±5.61 | 22.80±10.15 | 21.13±6.15 | 11.44±2.24* | 18.25±5.96 | 20.53±7.06 |
| M/F | 37/5 | 11/2 | 41/4 | 7/3 | 41/5 | 7/2* | 19/1 | 28/6* |
| Breech prevalence (%) | 31/35(88.57) | 9/10(90.00) | 32/36(88.88) | 8/9(88.88) | 35/40(87.50) | 5/6(83.33)* | 17/18(94.44) | 23/27(85.18)* |
| Height(cm) | 145.77±15.41 | 137.00±14.9*8 | 145.62±15.58 | 135.05±13.32* | 147.34±13.98 | 125.11±9.27* | 140.42±18.01 | 145.85±14.13 |
| -SDS Height | −3.36±1.89 | −5.02±2.32* | −3.44±2.01 | −5.09±2.07* | −3.79±2.26 | −3.56±1.04 | −4.17±2.31 | −3.54±1.98 |
| RUL | 0.94±0.07 | 0.95±0.07 | 0.93±0.06 | 0.98±0.04* | 0.94±0.07 | 0.99±0.04 | 0.95±0.07 | 0.94±0.06 |
| RAH | 0.97±0.16 | 0.98±0.03 | 0.97±0.15 | 0.98±0.03 | 0.97±0.15 | 1.02±0.08 | 0.94±0.22 | 0.99±0.03 |
| Bone age(year) | 12.18±3.03 | 12.62±2.70 | 12.12±2.90 | 13.00±3.12* | 13.05±2.09 | 8.33±3.54* | 11.10±3.32 | 12.98±2.52* |
| Basal GH(ug/L) | 0.12±0.23 | 0.14±0.23 | 0.11±0.22 | 0.16±0.26 | 0.07±0.04 | 0.43±0.48* | 0.19±0.29 | 0.05(0.05–0.05) |
| GH peak 1(ug/L) | 0.15±0.26 | 0.16±0.26 | 0.14±0.25 | 0.19±0.29 | 0.09±0.12 | 0.47±0.48* | 0.22±0.31 | 0.05(0.05–0.09) |
| GH peak 2(ug/L) | 0.14±0.27 | 0.40±1.14 | 0.13±0.26 | 0.49±1.30 | 0.08±0.10 | 0.80±1.38 | 0.36±0.93 | 0.05(0.05–0.06) |
| TSH (uIU/ml) | 5.19±4.07 | 3.67±1.62 | 5.04±3.97 | 3.86±1.66 | 4.90±3.67 | 4.47±3.96 | 4.55±3.14 | 4.88±4.01 |
| FT4 (pmol/L) | 8.01±1.55 | 11.73±1.39* | 8.42±1.72 | 10.96±2.88* | 8.66±2.00 | 10.03±2.84 | 8.91±2.36 | 8.89±2.14 |
| ACTH(pmol/L) | 3.62±1.69 | 4.27±2.44 | 3.68±1.94 | 4.14±1.57 | 3.75±1.96 | 3.87±1.45 | 3.37±1.78 | 4.02±1.93 |
| ACTH peak(pmol/L) | 3.96±2.29 | 5.39±2.82 | 4.02±2.28 | 5.64±3.02 | 4.45±2.57 | 3.42±1.68 | 3.97±2.25 | 4.53±2.66 |
| F8 am(nmol/L) | 80.05±69.93 | 181.51±120.25* | 67.25±50.78 | 269.53±55.67* | 85.88±78.71 | 196.83±114.40* | 98.01±95.97 | 109.63±94.46 |
| T(ng/ml) | 0.52±0.30 | 0.75±0.76 | 0.51±0.29 | 0.86±0.85 | 0.51±0.29 | 0.92±0.89* | 0.66±0.63 | 0.52±0.28 |
| E2(pg/ml) | 42.27±19.08 | 51.65±20.53 | 41.79±17.04 | 55.24±25.48 | 44.17±18.33 | 47.31±26.54 | 37.47±4.82 | 50.70±22.11* |
| LH(mIU/ml) | 0.11±0.13 | 0.85±2.04 | 0.10±0.12 | 1.08±2.28* | 0.13±0.16 | 1.06±2.45* | 0.20±0.37 | 0.07(0.07–0.11) |
| LH Peak(mIU/ml) | 0.48±0.85 | 6.90±19.57* | 0.43±0.78 | 9.03±22.11* | 0.62±1.03 | 9.04±23.59* | 0.98±1.86 | 0.11(0.26–0.68) |
| PRL(ug/L) | 18.09±10.71 | 13.53±5.51 | 17.63±10.51 | 14.20±5.85 | 16.61±9.37 | 18.90±12.54 | 27.44±7.08 | 10.84±4.72* |
*
P<0.05 compared to control group.
ACTH: adrenal corticotropic hormone. E2: estradiol. F: female. F 8 am: cortisol at 8 am. FT4: free thyroxin. GH: growth hormone. LH: luteinizing hormone. M: male. PRL: Prolactin. RAH: ratio of armspan to height. RUL: ratio of upper body segment to lower body segment. SDS: standard deviation scores. TSH: thyroid-stimulating hormone. T: testosterone.