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. 2013 Jan 14;8(1):e53572. doi: 10.1371/journal.pone.0053572

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© 2013 Tsuruyama et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A, B) Target DNA x_ky_k bound to HIV-1 integrase forming a loop-like structure or (C) a figure-eight-like structure. (D) DNA showing no HIV-1 integrase binding, where the arrow indicates unbound integrase. (E) Control experiment using x′_ky′_k including a ScaI digestion site AGTGACT. Bars indicate scale.