Fig. 10.

Fano factor measured from responses to low (250 pps) and high (5,000 pps) pulse rates. A: simulation results using the point process model. Results for the low pulse rate stimulation (blue line) are predicted by the Fano factor for a binomial distribution (black line, see text for details). Gray line shows the corresponding prediction of a binomial distribution for the 5,000-pps pulse train. Green line illustrates that simulated responses to the 5,000-pps pulse train can have larger Fano factors than responses to the 250-pps pulse train if the refractory period is shortened (τ_θ = 200 μs). Fano factor values are estimated from 100 intervals of simulated spike trains, where each interval is 100-s long. Error bars represent SE of these estimates. B: medians of Fano factors recorded from cat AN fibers. Numbers express the ratios of the median Fano factors for the 5,000-pps stimulus in proportion to the median Fano factors for the 250-pps stimulus. [Reproduced from Fig. 9 in Miller et al. (2008) with kind permission from Springer Science & Business Media: J Assoc Res Otolaryngol.]