Table 1.

Human pancreatic cell lines used in this study and a summary of VSV-ΔM51-GFP susceptibility and expression of select mRNAs.

Human cell line	Origina	VSV-ΔM51 resistancec	IRF7			IFN-α			IFN-β			IFN-λ			MxA			OAS
			Lowd	Highe	VSVf	Low	High	VSV	Low	High	VSV	Low	High	VSV	Low	High	VSV	Low	High	VSV
Capan-1	liver metastasis	−	x			x			x			x		x	x			x
MIA PaCa-2	primary PDA	−	x		x	x			x			x		x	x			x
Panc-1	primary PDA	−		x		x			x		x	x		x	x			x
Capan-2	primary PDA	−		x			x		x		x	x		x	x			x
AsPC-1	ascites	−		x			x		x		x	x		x	x			x		x
Suit2	liver metastasis	−		x			x		x		x	x		x		x	x	x		x
T3M4	LN metastasisb	−		x			x		x		x	x		x		x	x		x
HPDE	Non-malignant	+		x			x		x		x	x		x		x			x
CFPAC-1	primary PDA	++		x			x		x		x	x		x		x	x		x
HPAC	primary PDA	++		x			x		x		x	x		x		x			x
Hs766T	LN metastasis	+++		x			x		x		x	x		x		x			x
HPAF-II	primary PDA	+++		x			x		x		x	x		x		x			x

^aAll cell lines (except for non-malignant HPDE) have PDA origin

^bLN, lymph node

^c−, susceptible; +, intermediate; ++, resistant; +++ highly resistant

^dmRNA expression undetectable or barely detectable

^emRNA robustly expressed

^fmRNA expression increases upon VSV-Δ M51-GFP infection