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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Ann Biomed Eng. 2012 Sep 22;41(2):250–262. doi: 10.1007/s10439-012-0658-5

Figure 1.

Figure 1

Multishear microfluidic flow assay (msMFA) for high-content evaluation of shear dependent platelet function. (A) The msMFA is a six channel device reversibly bonded to a glass slide containing micropatterned CTF. The average wall shear rate in the channels from bottom to top is 50, 90, 170, 320 470, and 920 s−1. (B) Immunofluorescence of 50 μm CTF spots within two of the msMFA channels. The dotted white line indicates the position of the walls of the channel. Scale bar = 50 μm. (C) Platelet aggregates on spots following a 5 min. flow assay of thrombin inhibited whole blood. Platelets are labeled with an anti-CD41 antibody (blue). Scale bar = 50 μm.