Fig. 4.
Enhanced TS-EPSCs with 5-HT2CR activation occur in presence of GABAA receptor blockade. A: representative example of TS-EPSCs evoked in the presence of gabazine and the 5-HT2CR agonist CP809101 (50 μM). Application of gabazine did not prevent the increase in TS-EPSC amplitude by CP809101. B: average amplitude for each TS-EPSC stimulated at 0.5 Hz for gabazine (GZ), gabazine + CP809101 (GZ+CP), and wash. CP809101 significantly increased TS-EPSC amplitude from control. *P < 0.05. C: time course of the example shown in A. Lower case letters in A and C depict the time of representative examples, evoked at 0.5 Hz. Other time points were recorded at 0.1 Hz.