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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Immunogenetics. 2012 Nov 6;65(2):145–156. doi: 10.1007/s00251-012-0661-x

Figure 2. Ohnologs of genes located in the RGS1/RGS16 region.

Figure 2

According to phylogenetic analysis, 35 out of 76 genes located around RGS1 and RGS16 in human have copies on the different MHC paralogons, confirming that this region constitutes an extension of the paralogon on the human chromosome 1. The highest number of ohnologs could be retrieved from the MHC paralogon split between genomic locations 9q32-34 and 5q11-23. These results represent a phylogenetic analysis with the maximum likelihood method and bootstrap value 1000. * - The gene GLRX was not amongst the closest paralogs of GLRX2 according to our phylogenetic analysis, yet it was shown as the only paralog found in the database. ** Since phylogenetic analysis indicates that MR1 is rather a recent duplicate of the classical MHC molecules than an ancient paralog, it is linked to those genes by a dashed line on the figure.