Table 1.
Variable | Island (−) n=203 |
Islands (+) n=58 |
P value |
---|---|---|---|
Age (y); median (range) | 69 (37–92) | 68.5 (47–83) | 0.253 |
Gender (F; %) | 126 (62.1) | 30 (51.7) | 0.173 |
Smoking History (Pack-year); median (range) | 30 (0–730) | 40 (0–140) | 0.060 |
Tumor size (cm); median (range) | 2.3 (0.6–15.0) | 2.05 (0.4–6.5) | 0.283 |
Specimen type (wedge resection; %) | 66 (32.5) | 16 (27.6) | 0.524 |
pT (%) | 0.949 | ||
1a | 82 (40.4) | 22 (37.9) | |
1b | 44 (21.7) | 15 (25.9) | |
2a | 57 (28.1) | 16 (27.6) | |
2b | 7 (3.4) | 1 (1.7) | |
3 | 13 (6.4) | 4 (6.9) | |
pN (%) | 0.609 | ||
N0 | 173 (85.2) | 49 (84.5) | |
N1 | 17 (8.4) | 6 (10.3) | |
Nx | 13 (6.4) | 3 (5.2) | |
AJCC Stage | 0.960 | ||
IA | 116 (57.1) | 35 (60.4) | |
IB | 53 (26.1) | 13 (22.4) | |
IIA | 18 (8.9) | 5 (8.6) | |
IIB | 16 (7.9) | 5 (8.6) | |
Predominant Histological Pattern (%) | 0.003 | ||
Minimally invasive adenocarcinoma | 29 (14.3) | 2 (3.5) | |
Lepidic | 34 (16.8) | 4 (6.9) | |
Acinar | 90 (44.3) | 25 (43.1) | |
Papillary | 21 (10.3) | 7 (12.1) | |
Micropapillary | 8 (3.9) | 6 (10.3) | |
Solid | 16 (7.9) | 13 (22.4) | |
Mucinous adenocarcinoma | 5 (2.5) | 1 (1.7) | |
Nuclear Grade (%) | 0.011 | ||
1 | 15 (7.4) | 0 (0) | |
2 | 104 (51.2) | 24 (41.4) | |
3 | 84 (41.4) | 34 (58.6) | |
Lymphatic invasion (%) | 45 (22.17) | 19 (32.76) | 0.119 |
Vascular invasion (%) | 23 (11.3) | 8 (13.8) | 0.646 |
Pleural invasion (%) | 34 (16.8) | 13 (22.4) | 0.336 |