Table 1.
Variable | Correlation With IL-6 |
Model 1 | Model 2 | Model 3 | Model 4 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||
B | SE B | P | B | SE B | P | B | SE B | P | B | SE(B) | P | ||
Neuroticism | −.03 | −0.06 | 0.02 | .019 | −0.03 | 0.02 | .257 | −0.05 | 0.02 | .035 | −0.04 | 0.02 | .101 |
Conscientiousness | −.07* | −0.08 | 0.02 | .001 | −0.08 | 0.02 | .001 | −0.07 | 0.02 | .003 | −0.06 | 0.02 | .010 |
Extraversion | .01 | 0.01 | 0.03 | .797 | − 0.01 | 0.03 | .975 | −0.01 | 0.03 | .999 | 0.02 | 0.03 | .405 |
Agreeableness | .06* | 0.06 | 0.03 | .020 | 0.04 | 0.03 | .156 | 0.03 | 0.03 | .279 | 0.01 | 0.03 | .933 |
Openness | −.04 | −0.05 | 0.03 | .044 | −0.04 | 0.03 | .169 | −0.03 | 0.03 | .187 | −0.03 | 0.03 | .181 |
C x N1 | −09*** | −0.06 | 0.02 | .007 | −0.05 | 0.02 | .013 | −0.05 | 0.02 | .024 | −0.04 | 0.02 | .058 |
Age | .13*** | 0.10 | 0.02 | .001 | 0.09 | 0.02 | .001 | 0.13 | 0.02 | .001 | |||
Male | −.06* | −0.04 | 0.05 | .368 | −0.03 | 0.05 | .484 | −0.08 | 0.05 | .094 | |||
Minority | −.01 | 0.10 | 0.09 | .255 | 0.06 | 0.09 | .523 | −0.01 | 0.08 | .991 | |||
Education | −.07* | −0.04 | 0.02 | .078 | −0.03 | 0.02 | .130 | −0.01 | 0.02 | .687 | |||
Blood Thinner | 21 *** | 0.20 | 0.06 | .001 | 0.14 | 0.05 | .011 | ||||||
Statin | .06* | 0.02 | 0.05 | .664 | 0.01 | 0.05 | .837 | ||||||
Steroid | .01 | −0.03 | 0.07 | .701 | 0.03 | 0.06 | .636 | ||||||
Comorbidity Count | .21*** | 0.06 | 0.02 | .001 | 0.03 | 0.02 | .103 | ||||||
Average Alcohol Use | .06* | −0.01 | 0.03 | .767 | |||||||||
Former Smoker | .03 | 0.05 | 0.05 | .324 | |||||||||
Current Smoker | .07** | 0.20 | 0.07 | .004 | |||||||||
BMI | .21*** | 0.24 | 0.02 | .001 | |||||||||
R 2 | .03 | .09 | .13 | .21 | |||||||||
F for change in R2 | 5.40*** | 9.60*** | 10.72*** | 14.76*** |
Note. Personality traits, age, education, alcohol use, and BMI are in standard deviation units. Former and current smoking status was referenced to those who never smoked. All models were adjusted for the time interval between personality assessment and completion of biomarkers subproject questionnaires.
FDR adjustment for interaction term = p < 0.10.