Table 2.
Characteristics of patients with ulcerative colitis, and the relationship between QT prolongation n (%)
|
UC QT prolongation |
Test values |
|||
| - | + | χ2 | P value | |
| Diagnosis period (yr) | 44.13 ± 42.60 | 45.67 ± 47.99 | 0.86 | |
| Family history | 0.48 | 0.78 | ||
| None | 41 (77.4) | 6 (66.7) | ||
| UC | 8 (15.1) | 2 (22.2) | ||
| Colon cancer | 4 (7.5) | 1 (11.1) | ||
| Operation | 0.17 | 0.67 | ||
| Yes | 1 (1.9) | - | ||
| No | 52 (98.1) | 9 (100) | ||
| Extent of disease | 3.49 | 0.32 | ||
| Rectosigmoid | 16 (30.18) | 2 (22.22) | ||
| Left sided colon | 10 (18.86) | 4 (44.4) | ||
| Extensive | 6 (11.32) | - | ||
| Pancolitis | 21 (39.62) | 3 (33.3) | ||
| Clinical activity | 2.19 | 0.33 | ||
| TW1 (mild activity) | 34 (64.15) | 8 (88.89) | ||
| TW2 (moderate activity) | 17 (32.07) | 1 (11.11) | ||
| TW3 (severe activity) | 3.77 | - | ||
| Drug use | 0.09 | 0.75 | ||
| Used | 45 (84.9) | 8 (88.89) | ||
| Not used | 8 (15.09) | 1 (11.11) | ||
| 5-ASA | 0.19 | 0.65 | ||
| Used | 9 (16.98) | 1 (11.11) | ||
| Not used | 44 (83.01) | 8 (88.89) | ||
| CS | 1.12 | 0.28 | ||
| Used | 47 (88.67) | 9 (100) | ||
| Not used | 6 (11.32) | - | ||
| IS | 0.13 | 0.71 | ||
| Used | 49 (92.45) | 8 (88.89) | ||
| Not used | 4 (7.54) | 1 (11.11) | ||
| Smoking | 2.99 | 0.22 | ||
| Yes | 12 (22.64) | 2 (22.2) | ||
| No | 26 (49.05) | 2 (22.2) | ||
| Quit | 15 (28.30) | 5 (55.56) | ||
| Alcohol | ||||
| Yes | 9 (16.98) | 2 (22.2) | 0.46 | 0.79 |
| No | 42 (79.24) | 7 (77.78) | ||
| Quit | 2 (3.77) | - | ||
χ2 test, Mann-Whitney U test. TW: Truelove-Witts clinical activity index; UC: Ulcerative colitis; 5-ASA: 5-aminosalicylic acid; CS: Corticosteroid; IS: Immunosuppressive.