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. 2012 Dec 7;32(1):86–99. doi: 10.1038/emboj.2012.328

Figure 2.

Figure 2

Sudden cell rupture occurs following cytoplasmic NLRC4/Naip5 agonist expression. Upper left: plasma membrane (PM) staining, upper right: EGFP signal, lower left: YFP signal, lower right: transmitted white light (Trans). (A) PM stained C34 cells gain EGFP signal with time then rupture releasing cellular contents. Arrows highlight the release of cellular contents detected by transmission microscopy and PM staining. (B) PM surface stained C19 cells gain EGFP signal with time but fail to rupture and die. Data are representative of ⩾100 independent cell events. Scale bar 10 μm.