Table 2.
Effect of TEA in the relaxant effect of KA-acetoxy.
| Phenylephrine 10 (μM) | E max | pD2 |
|---|---|---|
| (condition) | (%) relaxation | (value) |
| Endothelium intact | 92.8 ± 3.7 | 6.0 ± 0.3 |
| Endothelium denuded | 95.2 ± 2.8 | 4.6 ± 0.2 |
| Endothelium intact + TEA (5 mM) | 90.7 ± 3.1a | 5.4 ± 0.4a |
| Endothelium denuded + TEA (5 mM) | 100 ± 0b | 4.4 ± 0.2b |
Values are expressed as means ± SEM of six experiments. The data were analysed by one-way Anova followed by the Bonferroni post-test.
aCompared to endothelium intact.
bCompared to endothelium denuded.