Table 1. Clinical summary of patients presentations and investigative work.

Patient number	1	2	3	4	5
Age at presentation	71 years	71 years	70 years	18 years	76 years
Ophthalmic presentation	Right granulomatous uveitis, progressing to bilateral vitritis	Left vitritis/vitreous infiltrate	Right granulomatous vitritis	Left hypopyon uveitis, haemorrhagic focal chorioretinitis at macula	Bilateral vitritis/vitreous infiltrate
Systemic presentation	Nil	Nil	Nil	Nil	Nil
Relevant past ocular and medical history	Pernicious anaemia	Type 2 diabetes mellitus	Hodgkin's lymphoma—in remission for 2 years	Nil	Testicular B-cell lymphoma
Investigations before diagnostic vitrectomy	Bloods and CXR—nil significant	Bloods and CXR—nil significant	Bloods & CXR—nil significant	Bloods, blood cultures, sputum cultures, CXR, abdominal US,-all nil significant	None
Treatment(s) before vitrectomy	Topical steroids & ocular antihypertensives Bilateral orbital floor steroid injections	None	None	None	None
Clinical diagnosis/suspicion	Idiopathic chronic vitritis	Intraocular lymphoma	Intraocular lymphoma	Endogenous fungal endophthalmitis	Intraocular lymphoma
Indication for vitrectomy	Exclude lymphoma	Exclude lymphoma	Exclude lymphoma	Investigate possible infective aetiologies	Exclude lymphoma
Interval from presentation to vitrectomy	8 months	2 months	1 month	2 days (initially refused all treatment)	1 month
Intra-operative complications	None	None	Retinal tear	Giant retinal tear	None
Postoperative complications	None	None	None	None	None
Investigations on vitrectomy specimen	Histopathology, PCR TEM	Histopathology microbiology PCR	Histopathology PCR	Histopathology, microbiology, PCR TEM	Histopathology PCR

Abbreviations: CXR, chest X-ray; PCR, polymerase chain reaction; TEM, transmission electron microscopy; US, ultrasound.