Table 2.
Current symptoms among neuropathologic groups
| Symptoms | bvFTD-FTLD, n (%) | bvFTD-AD, n (%) | Significance (χ2) | τ-Positive, n (%) | τ-Negative, n (%) | Significance (χ2) |
|---|---|---|---|---|---|---|
| Memory | 65 (87.8) | 21 (100) | NS | 20 (86.9) | 45 (88.2) | NS |
| Judgment and problem-solving | 73 (98.6) | 21 (100) | NS | 23 (100) | 50 (98.0) | NS |
| Language | 66 (89.2) | 18 (85.7) | NS | 19 (82.6) | 47 (92.1) | NS |
| Visuospatial | 40 (54.1) | 16 (76.2) | NS | 11 (47.8) | 19 (37.3) | NS |
| Attention/concentration | 57 (77.0) | 18 (85.7) | NS | 18 (78.2) | 39 (76.4) | NS |
| Apathy/withdrawal | 54 (73.0) | 15 (71.4) | NS | 17 (73.9) | 37 (72.5) | NS |
| Depression | 32 (43.2) | 12 (57.1) | NS | 10 (43.5) | 22 (43.1) | NS |
| Psychosis | 11 (14.9) | 6 (28.5) | NS | 4 (17.3) | 7 (13.7) | NS |
| Disinhibition | 49 (66.2) | 14 (66.7) | NS | 17 (73.9) | 32 (62.7) | NS |
| Irritability | 27 (36.5) | 13 (61.9) | NS | 8 (34.7) | 19 (37.2) | NS |
| Agitation | 25 (33.8) | 12 (57.1) | NS | 7 (30.4) | 18 (35.3) | NS |
| Personality change | 58 (78.3) | 11 (52.4) | 4.33; p < 0.05 | 18 (78.2) | 40 (78.4) | NS |
| Gait disorder | 39 (52.7) | 7 (33.3) | NS | 9 (39.1) | 30 (58.8) | NS |
| Falls | 24 (32.4) | 7 (33.3) | NS | 6 (26.1) | 18 (35.3) | NS |
| Tremors | 21 (28.4) | 8 (38.1) | NS | 6 (26.1) | 15 (29.4) | NS |
| Slowness | 37 (50) | 8 (38.1) | NS | 10 (43.5) | 27 (52.9) | NS |
Abbreviations: AD = Alzheimer disease; bvFTD = behavioral variant frontotemporal dementia; FTLD = frontotemporal lobar degeneration.