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. Author manuscript; available in PMC: 2013 May 2.
Published in final edited form as: Cell Stem Cell. 2012 Nov 2;11(5):701–714. doi: 10.1016/j.stem.2012.07.018

Figure 4. Pathway enrichment analysis of pair-wise comparisons between major developmental hematopoietic groups.

Figure 4

(A) GSEA of pair-wise comparisons to find GO Biological Processes enriched (red) or depleted (blue) between developmental populations. (B) GSEA of pair-wise comparisons to identify NetPath-annotated signaling pathways transcriptionally activated or suppressed. “In vivo Definitive HSC” includes WBM, FL12 F, E13.5 FL and E14.5 FL; “Specifying HSC” includes AGM, FL12 A, and placenta; “YS-like” includes EB and YS; and “All definitive HSC” includes ESC-HSC, WBM, FL12 F, E13.5 FL and E14.5 FL. Only significant gene sets are shown (Family wise error rate<0.05). See also Figure S4.