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. Author manuscript; available in PMC: 2013 Jan 15.
Published in final edited form as: Trends Neurosci. 2007 Dec 3;31(1):20–26. doi: 10.1016/j.tins.2007.10.004

Figure 2.

Figure 2

Schematic representation of the double negative feedback loops between miRNAs and transcription factors. (a) In ASEL sensory neurons in C. elegans, a high level of lsy-6 suppresses Cog-1, which controls the expression of miR-273. (b) In ASER, a high level of miR-273 suppresses Die-1, a transcription factor required for lsy-6 expression.