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Characteristics of scFvs that target FAP
| Round | ScFv clones picked | ScFv-positive binders by ELISA, >5× baseline | Mean ELISA [OD (range)] | ScFvs cloned | ScFvs expressed | ScFvs inhibiting FAP enzymatic activity |
|---|---|---|---|---|---|---|
| 2 | 192 | 48 | 0.853 (0.45–2.55) | 29 | 25 | 1 |
| 3 | 192 | 67 | 0.976 (0.44–4.86) | 24 | 15 | 0 |
