Figure 6.

Localization of three prostanoid receptor genes only in the scalp hair follicle dermal papilla and CTS. Amplified poly(A⁺)RNA from isolated scalp follicle components (A) from 3 individuals showed varying expression of prostanoid receptors despite equal expression of β-actin (B). With primers detecting native FP and all altFPs, three bands were seen only in isolated mesenchyme-derived tissues, the dermal papilla (DP), and the CTS surrounding the hair bulb (B). None were visible in the hair bulb matrix (M), the bulge (B), or the remaining lower follicle (LF). With specific primers for each gene, native FP, altFP1, and altFP4 were also only detected in the dermal papilla and CTS (see Table 1).