Figure 2.
(A) pH- and diol- responsive paclitaxel (PTX) release profiles of BCM4 by treating with diols (mannitiol and glucose) and/or pH 5.0 at 5hr compared with that of NCM. (B) MTT assays showing the viability of SKOV-3 cells after 1hr incubation with Taxol®, PTX-NCM and PTX-BCM4 with or without treatment with 100 mM mannitol at pH5.0, followed by 3 times wash with PBS and additional 23hr incubation. *: p < 0.05, **: p < 0.01, ***: p < 0.001.