Table 3.

Odds ratios (ORs) and 95% confidence intervals (CI) for risk of breast cancer associated with plasma level of Q10 and stratified by menopausal status, a nested case-control study within the Shanghai Women’s Health Study (SWHS), 1997–2006.

		OR (95% CI) by quintile of plasma concentration of CoQ10
	Case- control pairs	Q11	Q21	Q31	Q41	Q51	P for trend
		All women
	340	1.55 (0.97–2.48)	1.14 (0.72–1.80)	1.00 (Ref)	1.11 (0.71–1.74)	0.97 (0.60–1.60)	0.09
		Women with cases diagnosed > 1 year after blood draw
	303	1.90 (1.14–3.16)	1.41 (0.87–2.30)	1.00 (Ref)	1.15 (0.71–1.87)	1.13 (0.66–1.91)	0.03
		OR (95% CI) by menopausal status and quartile of CoQ10
		Q12	Q22	Q32	Q42	P for Trend
		Premenopausal women3
All	171	1.62 (0.91–2.89)	1.38 (0.78–2.44)	1.00 (Ref)	1.15 (0.65–2.02)	0.16
>1 year	152	1.89 (1.01–3.54)	1.70 (0.91–3.16)	1.00 (Ref)	1.25 (0.68–2.32)	0.09
		Postmenopausal women3
All	169	1.35 (0.79–2.28)	1.04 (0.58–1.88)	1.00 (Ref)	0.96 (0.52–1.79)	0.24
>1 year	151	1.71 (0.95–3.09)	1.14 (0.60–2.15)	1.00 (Ref)	1.15 (0.59–2.23)	0.14

¹20^th, 40^th, 60^th and 80^th percentiles were 429.0, 536.0, 629.0, and 796.0 ng/ml, respectively for all subjects.

²25^th, 50^th, and 75^th percentiles were 417, 537, and 665 ng/ml respectively for premenopausal women; and 517.5, 633, and 825 ng/ml respectively for postmenopausal women.

³P for interactions was 0.40.

A conditional logistic regression model was used whereby controls were matched to the index case by age, menopausal status at baseline, date of sample collection, time of sample collection, time interval after the last meal, and recent antibiotic use and additionally adjusted for age at 1^st live birth (continuous).