TABLE 1.

Functional analysis of P-gp in mitochondria isolated from rPCECs by flow cytometry. The analyses were performed with isolated mitochondria to evaluate the accumulation of Rho-123 alone and in presence of CsA. Mean fluorescence of Rho-123 (accumulation) was determined by flow cytometry after 30 minutes and was expressed as percentages of the mean fluorescence of the control mitochondria. The results are reported as a mean ± SD of three independent analyses.

Sample	Rho-123 accumulation (mean fluorescence in percent of the control)>
(A) Untreated mitochondrial	-
(B) Rho-123 alone (control)	100
(C) Rho-123 + CsA (10μM)	146.87±3.5