Table 3.
Multivariate Cox regression analysis on disease-specific survival in 80 invasive breast cancer patients
|
Disease specific survival | |||||
|---|---|---|---|---|---|
| Characteristics | β | SE | HR | 95% CI | P-value* |
| BRE grade |
0.14 |
0.17 |
1.16 |
0.83-1.61 |
0.39 |
| HER2/neu status |
0.18 |
0.40 |
0.83 |
0.39-1.80 |
0.64 |
| Axillary lymph node status |
0.03 |
0.35 |
1.03 |
0.53-2.04 |
0.64 |
| Pathologic tumor size |
0.001 |
0.01 |
0.10 |
0.98-1.02 |
0.97 |
| ER/PR status |
0.03 |
0.35 |
0.99 |
0.49-1.95 |
0.94 |
| CCNB2 | 1.82 | 0.61 | 6.14 | 1.87-20.1 | 0.003 |
* Determined by chi-square test.
β: Regression coefficient; SE: standard error of β; HR: hazard ratio; and CI: confidence interval. BRE: Bloom, Richardson, Elston/ Ellis; ER/PR: Estrogen/progesterone receptor. Coding of characteristics: BRE, HER2/neu status, Axillary lymph node status, ER/PR and CCNB2 were coded as 0 (negative) and 1 (positive) respectively. Pathologic tumor size was coded as 1 (0-20mm), 2 (>20-50mm), and 3 (>50mm).