Table 1.

Np_open and unitary conductance of WT and mutant channels in the various membrane lipid conditions (n = 3–9)

Sample	Lipid	Npo	±SEM	g, pS	±SD
WT	PG	0.08	±0.04	160	±22
	PC	0.01	±0.01	27	±8
	PGin/PCout	0.13	±0.04	212	±18
	PCin/PGout	0.01	±0.00	119	±8
E71A	PG	0.88	±0.01	179	±8
	PC	0.07	±0.03	57	±7
	PS	0.88	±0.04	169	±9
	PA	0.94	±0.03	181	±7
	EPC	0.03	±0.01	22	±6
	PGin/PCout	0.85	±0.02	106	±8
	PCin/PGout	0.08	±0.03	57	±6
	PSin/PCout	0.93	±0.01	159	±8
	PAin/PCout	0.91	±0.02	170	±6
	EPCin/PCout	0.04	±0.00	22	±7
	PGin/Pcout (pH 4.0in/out)	0.92	±0.03	193	±7
	PGin/Pcout (pH 4.0in/out)	0.11	±0.06	80	±7
	PG (pH 3.0)	0.91	±0.00	183	±7
	PG (pH 5.0)	0.77	±0.02	195	±9
	PG (pH 6.0)	0.05	±0.01	193	±8
	PC (pH 3.0)	0.34	±0.03	98	±6
E71A C-His Tag	PG	0.84	±0.04	202	±7
R11Q	PG	0.59	±0.04	213	±8
K14Q	PG	0.68	±0.05	197	±9
R11Q/K14Q	PG	0.26	±0.09	200	±8
R19Q	PG	0.79	±0.04	190	±9
H20Q	PG	0.72	±0.05	191	±9
M0-4Q	PG	0.26	±0.02	182	±11
	PG (pH 3.0)	0.16	±0.03	148	±13
	PG (pH 5.0)	0.44	±0.08	181	±10
H25Q/R27Q	PG	0.89	±0.02	226	±7
Δ10	PG	0.80	±0.05	162	±8
Δ22	PG	0.33	±0.03	149	±10
R52Q	PG	0.90	±0.01	187	±8
R64Q	PG	0.96	±0.01	164	±7
R89Q	PG	0.91	±0.01	178	±7
PSD-4Q	PG	0.90	±0.00	210	±8
ΔCPD	PG	0.75	±0.07	182	±16