Table 1.
Associations between estimated ambient occupational or residential benomyl exposures and PD risk in the UCLA PEG Study
| Exposure, n (%)* | Cases (n = 360) | Controls (n = 754) | OR (95%CI)† | P value‡ |
| Occupational | ||||
| No | 217 (60.3) | 531 (70.4) | Reference | |
| First quartile | 23 (6.4) | 55 (7.3) | 0.90 (0.53–1.53) | 0.69 |
| Second quartile | 26 (7.2) | 51 (6.8) | 1.07 (0.64–1.79) | 0.81 |
| Third quartile | 40 (11.1) | 62 (8.2) | 1.38 (0.88–2.17) | 0.16 |
| Fourth quartile | 54 (15.0) | 55 (7.3) | 1.97 (1.29–3.02) | 0.0017 |
| Trend P value | 0.0019 | |||
| Residential | ||||
| No | 209 (58.1) | 467 (61.9) | Reference | |
| First quartile | 31 (8.6) | 71 (9.4) | 0.87 (0.54–1.40) | 0.56 |
| Second quartile | 41 (11.4) | 72 (9.5) | 1.14 (0.73–1.77) | 0.57 |
| Third quartile | 31 (8.6) | 73 (9.7) | 0.79 (0.49–1.27) | 0.34 |
| Fourth quartile | 48 (13.3) | 71 (9.4) | 1.20 (0.78–1.86) | 0.40 |
| Trend P value | 0.071 |
CI, confidence interval; OR, unconditional logistic odds ratio.
*Exposure quartiles defined using distributions of exposed controls, separately for occupational or residential estimates. Two cases and one control with incomplete occupational data and one case with incomplete residential data were assumed to be unexposed.
†Adjusted for age (continuous), sex (male/female), smoking status (current/former/never), county (Fresno/Kern/Tulare, California), and education (<12 y/=12 y/>12 y).
‡For multiple testing considerations, 8 tests were performed so a P value of 0.006 was considered statistically significant.