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. 2012 Dec 24;110(2):612–617. doi: 10.1073/pnas.1219242110

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Fig. 3. — IL-7R transmits survival signals in CD8SP thymocytes through Bcl-2. (A) Expression of Bcl-2 in thymocyte fractions. 4SP and 8SP indicate TCRβ^hiCD25⁻Foxp3⁻CD4SP and TCRβ^hiCD8SP, respectively. Data represent five independent experiments with similar results. (B) Histograms (Upper) indicate expression of TCRβ in total thymocytes from mice of each genotype. Dot plots (Lower) show CD4 and CD8 expression in TCRβ^hi thymocytes. Bar graph (Right) shows the ratio of CD8SP to CD4SP cells in TCRβ^hi thymocytes (mean ± SEM, n = 8–11). (C) CD5 expression in TCRβ^hiCD8SP thymocytes from indicated mice. Data represent four independent experiments with similar results.