Table 3. Short selection of target mRNAs of the microRNAs with differences in expression between responders and non-responders to the energy-restricted.
| miRNA | Sequence | miRanda algorithm | TargetScan algorithm | |
| (source mirbase.org ) | MicroCosm | microRNA | TargetScan | |
| hsa-mir-935 | GGCGGGGGCGCGGGCGGCAGUGGCGGGAGCGGCCCCUCGGCCAUCCUCCGUCUGCCCAGUUACCGCUUCCGCUACCGCCGCCGCUCCCGCU | HDAC1, ADRA1A, LPL, RBP5 | HIF1A | ADRB1 |
| hsa-mir-223 | CCUGGCCUCCUGCAGUGCCACGCUCCGUGUAUUUGACAAGCUGAGUUGGACACUCCAUGUGGUAGAGUGUCAGUUUGUCAAAUACCCCAAGUGCGGCACAUGCUUACCAG | IGFL2c, DNMT1, HDAC2, HDAC8, SIRT5 | LIPG | IGF1R, HDAC4 |
| hsa-mir-224 | GGGCUUUCAAGUCACUAGUGGUUCCGUUUAGUAGAUGAUUGUGCAUUGUUUCAAAAUGGUGCCCUAGUGACUACAAAGCCC | MC3R, SREBF1 | ACAT1 | IRS2 |
| hsa-mir-376b | CAGUCCUUCUUUGGUAUUUAAAACGUGGAUAUUCCUUCUAUGUUUACGUGAUUCCUGGUUAAUCAUAGAGGAAAAUCCAUGUUUUCAGUAUCAAAUGCUG | FABP4, CPT2 | LIPH, PPARG, G6PC2, HDAC9, NR3C1 | HDAC9, IGF1R |
| hsa-mir-433 | CCGGGGAGAAGUACGGUGAGCCUGUCAUUAUUCAGAGAGGCUAGAUCCUCUGUGUUGAGAAGGAUCAUGAUGGGCUCCUCGGUGUUCUCCAGG | HDAC6, ADRA1A, IGFBP1, ACOX2, LPL, LIPE | GCLC, FRZB, | ADRA1A, LEPR |
| has-mir-154 | GUGGUACUUGAAGAUAGGUUAUCCGUGUUGCCUUCGCUUUAUUUGUGACGAAUCAUACACGGUUGACCUAUUUUUCAGUACCAA | ADRA1A, IGF1 | ||
| hsa-mir-27b | ACCUCUCUAACAAGGUGCAGAGCUUAGCUGAUUGGUGAACAGUGAUUGGUUUCCGCUUUGUUCACAGUGGCUAAGUUCUGCACCUGAAGAGAAGGUG | PPARG, INSR, MC4R, SIRT5 | SCD5, ACAT1, | PPARG, INSR, IRS1, CNR1, PPARGC1B, IGF1 |
| hsa-mir-409 | UGGUACUCGGGGAGAGGUUACCCGAGCAACUUUGCAUCUGGACGACGAAUGUUGCUCGGUGAACCCCUUUUCGGUAUCA | FZD3, PPARGC1A, APOF, AGPAT9 | ||
| has-mir-183 | CCGCAGAGUGUGACUCCUGUUCUGUGUAUGGCACUGGUAGAAUUCACUGUGAACAGUCUCAGUCAGUGAAUUACCGAAGGGCCAUAAACAGAGCAGAGACAGAUCCACGA | HDAC10, HDAC8, HDAC6, CRTC2, DGKH, GK5, PLB1, CPT2 | ACAD8 | PEX19 |
| hsa-mir-542-3p | UGUGACAGAUUGAUAACUGAAA | IGFBP1, IGFBP6, FABP3, PLA2G4B, LIPA, APOL5, ELOVL3, SLC27A3, PPARD, TNF | FABP3 | GDPD4, PLA2R1, |
| hsa-mir-4772-3p | CCUGCAACUUUGCCUGAUCAGA | ACSL1, PDK3, PPARGC1A, ERLIN2, IGF2BP1, IGF2, LRP8, CREBBP | ||
ACAD: acyl-CoA dehydrogenase family; ACAT: acetyl-coa acetyltransferase; ACOX: acyl-coenzyme A oxidase, peroxisomal; ACSL: acyl-CoA synthetase long-chain family member; ADRA1A: alpha-1A adrenergic receptor; ADRB1: beta-1 adrenergic receptor; AGPAT: 1-acylglycerol-3-phosphate o-acyltransferase; APO: apolipoprotein; CREBBP: CREB binding proteína; CNR: cannabinoid receptor; CPT: Carnitine O-palmitoyltransferase, mitochondrial precursor; CRTC: transducer of regulated cAMP response element-binding protein (CREB); DGKH : diacylglycerol kinase eta; DNMT: DNA (cytosine-5)-methyltransferase; ELOVL: elongation of very long chain fatty acids protein; ERLIN: ER lipid raft associated; FABP: fatty acid-binding protein, adipocyte; FRZB: frizzled-related protein; FZD: frizzled, drosophila, homolog of; GCLC: glutamate-cysteine ligase, catalytic subunit; GDPD: glycerophosphodiester phosphodiesterase domain containing; GIPR: gastric inhibitory polypeptide receptor; GK: glycerol kinase; G6PC: glucose-6-phosphatase, catalytic; HDAC: histone deacetylase; HIF1A: hypoxia-inducible factor; IGF1: insulin-like growth factor 1; IGF1R: insulin-like growth factor 1 receptor; IGFBP: insulin-like growth factor-binding protein precursor; IGFL2c: insulin growth factor-like family member 2 precursor; INSR: insulin receptor; IRS: insulin receptor substrate; LEPR: leptin receptor; LIPA: lysosomal acid lipase/cholesteryl ester hydrolase precursor; LIPE: hormone-sensitive lipase; LIPG: factor 1, alpha subunit; lipase, endothelial; LIPH: lipase h; LRP: Low density lipoprotein receptor-related protein, apolipoprotein e receptor;LPL: Lipoprotein lipase precursor; MCR: Melanocortin receptor; NR3C1: glucocorticoid receptor; PDK: pyruvate dehydrogenase kinase, isozyme; PEX: peroxisomal biogenesis factor; PLA2G4B: cytosolic phospholipase A2 beta; PLA2R1: phospholipase A2 receptor 1; PLB: phospholipase B; PPARD: Peroxisome proliferator-activated receptor delta; PPARG: Peroxisome proliferator-activated receptor gamma; PPARGC: peroxisome proliferator-activated receptor gamma, coactivator; RBP: retinol-binding protein, cellular; SLC27A: long-chain fatty acid transport protein; SCD: stearoyl-coa desaturase; SIRT5: NAD-dependent deacetylase sirtuin-5; SREBF1: sterol regulatory element-binding protein 1; TNF: tumor necrosis factor precursor.