Table 2.
NC | DM | DM-SE 0.4 | DM-SE 0.6 | DM-G | |
---|---|---|---|---|---|
Triglycerides (mmol/L) |
0.92±0.15a |
1.86±0.13b |
0.75±0.13a |
0.68±0.12a |
0.89±0.02a |
Total cholesterol (mmol/L) |
2.01±0.10a |
2.70±0.19b |
1.81±0.05a |
1.81±0.06a |
2.14±0.10a |
HDL-cholesterol (mmol/L) |
1.20±0.04a |
1.33±0.02a |
1.28±0.02a |
1.34±0.06a |
1.02±0.09b |
LDL-cholesterol (mmol/L) |
0.73±0.03a |
1.25±0.07b |
0.82±0.07a |
0.72±0.04a |
0.88±0.05a |
Glutamic oxaloacetic transaminase (IU/L) |
42.81±1.19 |
46.02±2.92 |
42.94±2.05 |
44.26±0.73 |
45.03±1.52 |
Glutamic pyruvic transaminase (IU/L) |
14.54±3.45 |
12.72±1.20 |
13.78±1.94 |
10.17±0.73 |
9.68±1.96 |
Glucose (mmol/L) |
1.18±0.06a |
1.67±0.12c |
1.51±0.07bc |
1.29±0.02b |
1.21±0.12a |
Insulin (pmol/L) |
3.73±0.27a |
1.25±0.20b |
1.64±0.26ab |
1.91±0.11ab |
3.69±1.46a |
AUC of glucose (mmol·min/L) | 748.25±27.39a | 1250.25±35.24c | 881.20±39.61b | 907.76±29.55b | 781.39±23.36a |
Values are expressed as mean ± SEM (n = 5); NC, normal control rats administrated saline; DM, rats with diabetes mellitus administrated saline; DM-SE 0.4, rats with diabetes mellitus administrated 0.4 g/kg body weight of sorghum extract; DM-SE 0.6, rats with diabetes mellitus administrated 0.6 g/kg body weight of sorghum extract; DM-G, rats with diabetes mellitus administrated 0.7 mg/kg body weight of glibenclamide; AUC, area under the curve during intraperitoneal glucose tolerance tests. The values in the rows with different letters were significantly different at p < 0.05 using ANOVA with Duncan’s multiple range test.