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. 2013 Jan 15;8(1):e54052. doi: 10.1371/journal.pone.0054052

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© 2013 Huang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Tsc1^flox/flox; cyp19-cre mice produced more pups than wild type mice. (B) The average litter size of Tsc1^flox/flox; cyp19-cre mice was bigger than that of the wild type. (C) Tsc1^flox/flox; cyp19-cre mice ovulated more oocytes than wild type mice in superovulation analysis. (D) A little more oocytes were collected from the oviduct of Tsc1^flox/flox; cyp19-cre mice than that from wild mice after natural ovulation and copulation.WT, wild type. *, P<0.05.