Table 1.

Microarray analysis of endothelial-associated genes expressed by cutaneous melanoma

Protein	Symbol/unigene	Function	Ratio*
CD31	PECAM/Hs.78146	Adhesion molecule	0.2
TIE-1	TIE/Hs.78824	Receptor tyrosine kinase	25.0
VE-cadherin	CDH5/Hs.76206	Cell–cell adhesion	10.7

^*cDNA microarray analysis was performed as described (8), comparing highly aggressive (C8161) vs. poorly aggressive (C81-61) human cutaneous melanoma cells from the same patient. Approximately 1,600 expressed sequence tags and known genes were differentially expressed from a total of 6,000.