Table 3.
Values of cough reflex sensitivity obtained in TRPM8 line of the study
| Saline | Vehicle | (+) Menthol | (−) Menthol | |
|---|---|---|---|---|
|
C2 | ||||
|
Cu |
11.8 |
12.7 |
26.5 * |
22.4* |
|
C2 GM |
12.5 |
14.7 |
31.3 * |
26.3* |
|
GSD |
4.6 |
2.7 |
5.9 |
6.1 |
|
CI min |
10.4 |
11.3 |
28.9 |
23.8 |
|
CI max |
14.7 |
17.2 |
33.6 |
28.7 |
|
C5 | ||||
|
GM |
261 |
249 |
458.5 |
478.8 |
|
GSD |
4 |
4.3 |
3.1 |
2.9 |
|
CI min |
259 |
248 |
456.8 |
477 |
| CI max | 263 | 251 | 460.2 | 480.5 |
Note: data are expressed in μM, GM – geometric mean, GSD – geometric standard deviation, CI min, CI max – 95% confidence intervals with alpha = 0.05. *p<0.05, Cu – urge to cough, C2 – concentration of capsaicin inducing 2 or more coughs, C5 concentration of capsaicin inducing 5 or more coughs.