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Response ratio of TLR4 reporter cells when applied with particles. The response ratio of TLR4 reporter cells after exposure to increasing concentration of particles (0, 12.5, 50 and 200 μg/ml) (grey line), spiked (0.3 EU/ml) particles (green line) and spiked particles + endotoxin inhibitor (polymyxin B sulfate, 100 μg/ml) (red line). A: TiO2 particles (non-baked and baked); B: CaCO3 particles (non-baked and baked); C: Ag particles (non-baked and baked); D: SiO2 particles (non-baked).
