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. 2012 Dec 22;12:617. doi: 10.1186/1471-2407-12-617

Table 1.

Primary information for 16 genotyped SNPs in oxidative pathway genes

Genotyped SNPs Location/or Amino acid change MAF for Chinese in databasea P value for HWE testb % Genotyping rate
GPX1: rs1800668 C>T
 Promoter
 0.078
 0.706
 99.1
CAT: rs769214 G>A
 5’region
 0.293
 0.275
 97.9
CAT: rs7943316 A>T
 5’region
 0.256
 0.822
 98.0
PON1: rs854552 T>C
 3' UTR
 0.179
 0.195
 99.1
PON1: rs662 G>A
 nsSNP/Q192R
 0.430
 0.424
 97.7
NQO1: rs10517 C>T
 3' UTR
 0.381
 0.397
 97.7
NQO1: rs1800566 T>C
 nsSNP/S1P
 0.478
 0.757
 97.5
MnSOD: rs4880 T>C
 nsSNP/V16A
 0.146
 0.914
 98.8
MnSOD: rs5746136 G>A
 3' UTR
 0.422
 0.264
 98.7
SOD3: rs2536512 G>A
 nsSNP/T58A
 0.100
 0.730
 98.6
SOD3: rs2695232 C>T
 3' UTR
 0.367
 0.284
 98.6
NOS1: rs2682826 C>T
 3' UTR
 0.256
 0.163
 98.0
NOS1: rs1047735 T>C
 nsSNP/Q902H
 0.488
 0.522
 98.4
NOS2: rs2297518 G>A
 nsSNP/L608S
 0.175
 0.426
 97.2
NOS2: rs10459953 G>C
 Promoter
 0.489
 0.790
 99.1
NOS3: rs1799983 G>T nsSNP/D298E 0.111 0.586 97.9

Abbreviations: MAF minor allele frequency, HWE Hardy-Weinberg equilibrium.

aMinor allele frequency in the Chinese (CHB, Han Chinese in Beijing, China) population, as reported in dbSNP database.

bP values were calculated from our control genotype.