Table 1. Reactivities and epitope mapping of monoclonal antibodies (mAbs) against HCV-LPs of genotypes 3a and 1b.
mAb | Epitopic region on E2 | WB | ELISA/Dotblot | Titer (HCV-LP 3a) | Titer (HCV-LP 1b) |
G2C7 | ND | − | ++ | Beyond 1024 | Beyond 1024 |
E8G9 | aa 555–699 | ++ | ++ | Between 256 and 512 | 256 |
H1H10 | ND | − | + | Between 8 and 16 | Between 8 and 16 |
D2H3 | aa 596–699 | + | + | Between 64 and 128 | Between 128 and 256 |
E1B11 | ND | − | + | 64 | 64 |