Table 4.
Multivariate analysis for ACE decrease and discontinuation
| ACE decrease* | ACE discontinuation | |||||||
|---|---|---|---|---|---|---|---|---|
| OR 95% CI | OR 95% CI | |||||||
| Sig | OR | Lower | Upper | Sig | OR | Lower | Upper | |
| Age | 0.01 | 1.80 | 1.08 | 2.99 | 0.03 | 1.45 | 1.03 | 2.04 |
| Gender | 0.34 | 4.05 | 0.28 | 56.8 | 0.79 | 0.73 | 0.08 | 6.99 |
| Idiopathic constipation | 0.99 | 9.73 | 0.54 | 175 | 0.05 | 16.8 | 0.97 | 280.6 |
| Months CM2 after ACE | 0.07 | 0.83 | 0.68 | 1.02 | 0.28 | 1.03 | 0.94 | 1.12 |
| GC Normalization | 0.61 | 2.63 | 0.20 | 34.4 | 0.30 | 1.96 | 0.22 | 17.73 |
| HAPC Normalization | 0.02 | 59.0 | 1.72 | 2025 | 0.29 | 0.33 | 0.04 | 2.62 |
*
Includes those that discontinued ACE use. HAPC’s, high amplitude propagating contractions; GC, gastrocolonic response; CM2, repeat colon manometry