Table 4.

Summary of hydrogen exchange predictions derived from X-ray, homology modeling and NMR structures

protein	method	PDB code	resolution	Δlog kOH−	correlation	rmsdc
ubiquitin	X-ray	a	1.00 Å	0.92	0.79	---
	X-ray	1YIW	1.39 Å	1.03	0.61	0.66 Å
	X-ray	1UBQ	1.80 Å	1.17	0.82	0.43 Å
	homology	1BT0	1.70 Å	1.44	0.61	0.61 Å
	NMR	1V80		1.52	0.12	1.10 Å
CI2	X-ray	1LW6	1.50 Å	0.83	0.83	---
	X-ray	2CI2	2.00 Å	1.04	0.77	0.46 Å
	X-ray	2SNI	2.10 Å	0.84	0.83	0.38 Å
	homology	1VBW	0.93 Å	1.38	0.76	1.15 Å
	NMR	3CI2		2.55	0.42	1.55 Å
	NMR	b		1.22	0.70	1.10 Å
FKBP12	X-ray	2PPN	0.92 Å	0.82	0.85	---
	X-ray	1D6O	1.85 Å	1.07	0.82	0.32 Å
	X-ray	1FKK	2.20 Å	1.14	0.85	0.40 Å
	homology	1YAT	2.50 Å	1.18	0.74	0.84 Å
rubredoxin	X-ray	1BQ8	1.10 Å	0.96	0.93	---
	X-ray	1VCX	1.50 Å	0.97	0.94	0.22 Å
	X-ray	1CAA	1.80 Å	1.03	0.93	0.15 Å
	homology	1IRN	1.20 Å	1.85	0.69	0.54 Å

^acited [27,30] but unpublished.

^bRECOORD analysis [78].

^crmsd for protein backbone with respect to the highest resolution X-ray structure.