Table 1.

Average daily values for energy balance parameters.

Parameter	Ad Lib Control	Ad Lib High Fat	DPCD	DPHF
Caloric Intake (kcals)	13.76 ± 0.20	13.66 ± 0.54	13.11 ± 0.33	13.45 ± 0.35
Energy Expenditure (kcals/hr)	0.49 ± 0.01	0.52 ± 0.01	0.45 ± 0.01*	0.48 ± 0.01
Energy Balance (net kcals/day)	2.20 ± 0.50	1.52 ± 0.44	2.16 ± 0.29	2.01 ± 0.31
RER	0.93 ± 0.00	0.85 ± 0.00$	0.92 ± 0.00*	0.85 ± 0.00#†

Non-invasive monitoring of energy balance parameters was performed using a CLAMS, in ad libitum control fed and ad libitum high fat fed mice, as well as mice fed either a high fat diet (DPHF) or a control fat diet (DPCD) during the dark phase (whereas no food was allowed during the light phase). Data are shown as daily averages across the entire study duration. Values are expressed as mean ± SEM (n=6).

^*denotes p<0.05 for ad libitum high fat versus DPCD

^$denotes p<0.05 for ad libitum control versus ad libitum high fat

^#denotes p<0.05 for DPCD versus DPHF

^†denotes p<0.05 for ad libitum control versus DPHF.