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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Invest Dermatol. 2012 Oct 25;133(2):325–333. doi: 10.1038/jid.2012.393

Figure 3. Overview of retinoid metabolism and how these proteins changed during the progression of cicatricial alopecia.

Figure 3

The left shows a schematic of RA synthesis, degradation, and signalling pathways in B6 mice. The right shows a summary of IHC results in chow fed B6 mice with no (control), mild, moderate, or severe disease. Immunoreactivity intensity ranges from dark to light; very strong (maroon), strong (red), moderate (hot pink), mild (pink), or undetectable (white). CL= companion layer, PM= premedulla.