Table 2.
Trial | Treatment arm | Observed Data | Adjusted Means and Treatment Effect (± SE or with 95% CI) | |||||
---|---|---|---|---|---|---|---|---|
Mo 0 | Mo 4 | Mo 12 | Mo 4 | Mo 12 | ||||
Mo 4 vs Mo 0 | 6x/wk vs. 3x/wk | Mo 12 vs Mo 0 | 6x/wk vs. 3x/wk | |||||
Daily Trial* | 3x/wk | 87 ± 10 | 88 ± 10 | 89 ± 9 | +1.1 ± 0.7 | −0.0 (−1.8 to 1.5) | +1.9 ± 0.8 | +0.2 (−1.8 to 2.2) |
6x/wk | 87 ± 9 | 88 ±10 | 89 ± 10 | +1.0 ± 0.6 | +2.1 ± 0.7 | |||
Nocturnal Trial** | 3x/wk | 90 ± 6 | 94 ± 6 | 95 ± 4 | +3.5 ± 0.8 | −2.1 (−4.3 to 0.0) | +4.4 ± 1.1 | −2.3 (−5.4 to0.8) |
6x/wk | 90 ± 8 | 92 ± 10 | 93 ± 12 | +1.3 ± 0.8 | +2.1 ± 1.1 |
Note: Values for observed data are given as mean ± SD; other values given as adjusted mean ± SE or treatment effect (95% CI).
Values adjusted for baseline score and clinical center
Values adjusted for baseline score
Abbreviations: 3MS, Modified Mini-Mental State Examination; SD - standard deviation, SE - standard error, CI - confidence interval
The maximum (best) score on the 3MS is 100.