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Frequency of different substitution modes within CpG in the present cohort in comparison to previously reported mutations in the 3 analyzed sarcomeric genes
| Mode of substitution in CpG | Present study | Previously reported CpG substitutionsa |
|---|---|---|
| G > A | 15/27 = 55.6 % | 113/251 = 45 % |
| C > T | 6/27 = 22.2 % | 56/251 = 22.3 % |
| C > A | 3/27 = 11.1 % | 13/251 = 5.2 % |
| C > G | 0/27 = 0 % | 18/251 = 7.2 % |
| G > C | 2/27 = 7.4 % | 30/251 = 12.0 % |
| G > T | 1/27 = 3.7 % | 21/251 = 8.4 % |
a[46]
