. 2013 Jan 11;33(1):e00013. doi: 10.1042/BSR20120111

Table 3. Significance of change (P values) in auto-inactivation of each mutation compared with all data.

P values was calculated using an unpaired two-tailed Student's t test. All values were calculated using PRISM® GraphPad. See Table 2 for a detailed description of the chimaeras.

	GAD67_WT	GAD67_65CT	GAD67_{Tyr292Phe_ 65loop}	GAD67_{Tyr292Phe_65loop} _Val444Leu	GAD67_{Tyr292Phe_65loop_} _{Val444Leu_65CT}	GAD65_WT	GAD65_67CT	GAD65_{Phe283Tyr_} _67loop	GAD65_{Phe283Tyr_} _{67loop_Leu435Val}
GAD67_65CT	<0.0001
GAD67_{Tyr292Phe_65loop}	<0.0001	NO
GAD67_{Tyr292Phe_65loop_Val444Leu}	<0.0001	<0.0001	<0.0001
GAD67_{Tyr292Phe_65loop_Val444Leu_65CT}	<0.0001	<0.0001	<0.0001	0.0442
GAD65_WT	<0.0001	<0.0001	<0.0001	NO	NO
GAD65_67CT	NO	0.017	0.0416	<0.0001	0.0003	<0.0001
GAD65_{Phe283Tyr_67loop}	<0.0001	NO	NO	<0.0001	<0.0001	<0.0001	0.0317
GAD65_{Phe283Tyr_ 67loop_Leu435Val}	<0.0001	NO	0.0136	<0.0001	<0.0001	<0.0001	0.0052	NO
GAD65_{Phe283Tyr_ 67loop_Leu435Val_ 67CT}	NO	0.0013	0.0031	<0.0001	<0.0001	<0.0001	NO	0.0036	0.0003