Table 7.
Suspected adverse drug reactions (not leading to withdrawal in 76 dogs)
| Treatment Group | ||
|---|---|---|
| Suspected Adverse Drug Reactions | Pimobendan | Placebo |
| Gastrointestinal disorders (eg, emesis, diarrhea, inappetence) | 6 | 3 |
| Abnormal behavior (eg, lethargy, confusion, restlessness) | 1 | 2 |
| Head bobbing (transient) after administration of mexiletine, condition resolved | 1 | |
| Increased respiratory rate and effort with exercise | 1 | |
| Cough (unexplained cause) | 1 | |
| Mast cell tumor, left thorax | 1 | |
| Pulmonary mass and rectal mass | 1 | |
| Ventricular arrhythmia on Holter monitor recording | 1 | |
| Irregular and rapid heartbeats reported by owner | 1 | |
| Syncope | 4 | |
| Total | 9 | 14 |