TABLE 3.

Factors used in case scenarios

Factor	Level
Age (years)	55
	75
ECOG performance status	0 (fully active, able to carry on all predisease performance without restriction)
	2 (ambulatory and capable of all self-care but unable to carry out any work activities, up and about more than 50 % of waking hours)
Tumor presentation	Metachronous presentation with colon primary removed 25 months ago, adjuvant chemotherapy completed after colon resection
	Metachronous presentation with colon primary removed 11 months ago, adjuvant chemotherapy completed after colon resection
	Synchronous presentation with colon primary removed 1 month ago, no chemotherapy given
Tumor number and location	1 tumor in a single lobe of the liver
	1 tumor centrally located in the liver
	3 tumors in a single lobe of the liver
	3 tumors in both lobes of the liver
	5 tumors in a single lobe of the liver
	5 tumors in both lobes of the liver
Tumor size (largest metastasis) (cm)	2
	4
	6
Extent of resection required to remove all metastatic disease	30 % of liver
	45 % of liver
	60 % of liver
Extrahepatic disease	No extrahepatic disease
	Resectable solitary lung metastasis
	Metastatic disease to the hilar/hepato-duodenal lymph nodes

ECOG Eastern Cooperative Oncology Group